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PorX is an essential response regulator of the type IX secretion system associated with bacterial pathogenicity, gliding motility and metabolic enzyme secretion.

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PorX-BeF 3 and T272A-pGpG crystals were collected at the Se-absorption edge (0.97893 and 0.97923 Å, respectively), whereas PorX-HR data were collected at the Zn 2+ absorption edge (1.28202 Å).

Structure-function analysis of PorXFj, the PorX homolog from ...

The Type-IX secretion system (T9SS) is a nanomachinery utilized by bacterial pathogens to facilitate infection. The system is regulated by a signaling cascade serving as its activation switch. A pivotal member in this cascade, the response regulator protein PorX, represents a promising drug target to prevent the secretion of virulence factors.

The PorX/PorY system is a virulence factor of Porphyromonas ... - PubMed

PorX protein might be involved in the dynamics of the T9SS. Keywords: transcriptional regulation, type IX secretion, gingivitis, periodontitis, Porphyromonas gingivalis, two-component system, bacterial pathogenesis

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